I use and deeply, deeply love NNW myself. My feed categories, in top-to-bottom order:

- News: mostly feeds from dead tree newspapers and media outlets like CNN)

- Comics: a handful from Tapestry, linked in a comment above

- Mac: news, software update sites, rumors, pundits

- Security: scraped mailing list feeds, infosec news sites

- Tech: general tech news, CNet, Wired, etc

- Music: music review sites, a pretty small category at this point

- Weblogs: a relatively small selection of mostly personal blogs with the requisite BoingBoing, Fleshbot, Metafilter and the like for some group action

Despite the order, I tend to read the weblogs the most and the real news the least. Go figure.