Ape Escape 2. I come from the land down under, where the occasional top-quality PS2 platform game is released before it makes it to the States, and I can't recommend it highly enough, especially to anyone who enjoyed Ratchet and Clank. It's brainless without being repetitive, and that's a rare achievement.

And as obligatory a Jerkcity reference as this sounds, the Yellow Monkey boss is the closest we've come yet to seeing Pants in a video game.